ATG5 Ab
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ATG5 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ATG5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ATG5 Ab
Western blot analysis of ATG5 expression in Raji cell lysate.

产品简介

Product Introduction

Catalog No.

CY5766

Source

Recombinant Rabbit mAb

UniProt ID

Q9H1Y0

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

32 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; Apoptosis specific protein; ASP; ATG 5; ATG5 autophagy related 5 homolog; Autophagy protein 5; hAPG5;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ATG5

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity.

引用文献

Citation

Eliminating the invading extracellular and intracellular FnBp+ bacteria from respiratory epithelial cells by autophagy mediated through FnBp-Fn-Integrin α5β1 axis

期刊名称：

Frontiers in Cellular and Infection Microbiology

PMID：

38264727

影响因子：

4.6

应用范围：

WB,Pull Down

检测物种：

Mouse,Human

发表时间：

2024-01-09
A novel selective FAK inhibitor E2 inhibits ovarian cancer metastasis and growth by inducing cytotoxic autophagy

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

39102992

影响因子：

5.3

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-08-03

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CY5766

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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