NOX2 Ab
Instructions

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NOX2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NOX2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
NOX2 Ab
Western blot analysis of NOX2/CYBB/gp91phox expression in MCF-7 cell lysate.
NOX2 Ab
NOX2 Ab
NOX2 Ab
NOX2 Ab
NOX2 Ab

产品简介

Product Introduction

Catalog No.

CY5739

Source

Recombinant Rabbit mAb

UniProt ID

P04839

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

65 kDa

Observed Mol Weight

65 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

CGD; CGD91-phox; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NOX2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

引用文献

Citation

Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats

期刊名称：

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

PMID：

29923306

影响因子：

2.659

应用范围：

WB,IHC,ICC/IF

检测物种：

Rat

发表时间：

2018-06-19
Contribution of acid sphingomyelinase to angiotensin II-induced vascular adventitial remodeling via membrane rafts/Nox2 signal pathway

期刊名称：

LIFE SCIENCES

PMID：

30677425

影响因子：

3.448

应用范围：

IHC,WB,ICC/IF

检测物种：

Rat

发表时间：

2019-01-21
Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic rats

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

31369842

影响因子：

5.657

应用范围：

WB,ICC/IF,IHC

检测物种：

Rat

发表时间：

2019-07-29
Inhibition of vascular adventitial remodeling by netrin-1 in diabetic rats

期刊名称：

JOURNAL OF ENDOCRINOLOGY

PMID：

31846437

影响因子：

4.041

应用范围：

WB,IHC,ICC/IF

检测物种：

Rat

发表时间：

2020-03-01
Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma

期刊名称：

Cell Death Discovery

PMID：

33637687

影响因子：

5.241

应用范围：

WB

检测物种：

Human

发表时间：

2021-02-26
Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis

期刊名称：

Frontiers in Medicine

PMID：

34490303

影响因子：

5.093

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-08-19

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CY5739

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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