TCF7L2 Ab
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TCF7L2 Ab
Western blot analysis of TCF7L2 expression in Jurkat cell lysate.
TCF7L2 Ab
Immunohistochemical analysis of paraffin-embedded human colonic cancer, using TCF7L2 Antibody.
TCF7L2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab
TCF7L2 Ab

产品简介

Product Introduction

Catalog No.

CY5720

Source

Recombinant Rabbit mAb

UniProt ID

Q9NQB0

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

68 kDa

Observed Mol Weight

68 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

TCF7L2; HMG box transcription factor 4; HTCF-4; T-cell factor-4 variant X2; T-cell factor 4; Transcription factor 7-like 2; TCF-4;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TCF7L2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as a repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.

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CY5720

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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