p-STAT1 (S727) Ab

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p-STAT1 (S727) Ab

Instructions

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Phospho-STAT1 (S727) expression in HeLa cell lysate treated with etoposide.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded human lung cancer, using Phospho-STAT1 (S727) Antibody.

Introduction

Citation

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产品简介

Product Introduction

Catalog No.

CY5702

Source

Recombinant Rabbit mAb

UniProt ID

P42224

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

87 kDa

Observed Mol Weight

87 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

Signal transducer and activator of transcription 1; Transcription factor ISGF-3 components p91/p84; STAT1; CANDF7; ISGF3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human STAT1 around the phosphorylation site of S727

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.

引用文献

Citation

Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells via regulating miR-135a-5p/stat1 axis

期刊名称：

ACTA TROPICA

PMID：

37080266

影响因子：

2.7

应用范围：

检测物种：

Human

发表时间：

2023-04-18

Nocardia rubra cell wall skeleton regulates tumour-associated macrophage polarization by reprogramming M2 macrophages into M1 macrophages via STAT1/STAT6 pathways

期刊名称：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY

PMID：

38441254

影响因子：

3.7

应用范围：

IHC,ICC/IF,WB

检测物种：

Human

发表时间：

2023-08-11

hUC-MSCs therapy for Crohn’s disease: efficacy in TNBS-induced colitis in rats and pilot clinical study

期刊名称：

EBioMedicine

PMID：

38653187

影响因子：

9.7

应用范围：

IHC

检测物种：

Human

发表时间：

2024-04-22

Sodium Butyrate Alleviates Lipopolysaccharide-Induced Inflammation through JAK/STAT Signalling in Primary Human Corneal Fibroblasts

期刊名称：

EUROPEAN JOURNAL OF PHARMACOLOGY

PMID：

39271038

影响因子：

4.2

应用范围：

WB,ICC/IF

检测物种：

Human

发表时间：

2024-09-11

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CY5702

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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