eIF2A K2 Ab
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eIF2A K2 Ab
Western blot analysis of PKR expression in MCF-7 cell lysate.
eIF2A K2 Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using PKR Antibody.
eIF2A K2 Ab
Immunofluorescent analysis of Hela cells, using PKR Antibody.
eIF2A K2 Ab
eIF2A K2 Ab
eIF2A K2 Ab
eIF2A K2 Ab
eIF2A K2 Ab

产品简介

Product Introduction

Catalog No.

CY5665

Source

Recombinant Rabbit mAb

UniProt ID

P19525

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

62 kDa

Observed Mol Weight

68 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

eIF-2A protein kinase 2; Protein kinase RNA-activated; PKR; p68 kinase; P1/eIF-2A protein kinase;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human eIF2A K2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to viral infection.

引用文献

Citation

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

期刊名称：

CELL

PMID：

31031002

影响因子：

36.216

应用范围：

WB,IP

检测物种：

Human

发表时间：

2019-04-25
RNA circles with minimized immunogenicity as potent PKR inhibitors

期刊名称：

MOLECULAR CELL

PMID：

34951963

影响因子：

17.97

应用范围：

WB

检测物种：

Human

发表时间：

2021-12-23

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CY5665

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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