APC Ab
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APC Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
APC Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
APC Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
APC Ab
Western blot analysis of APC expression in 293T cell lysate.
APC Ab
Immunohistochemical analysis of paraffin-embedded human colon cancer, using APC Antibody.
APC Ab
APC Ab
APC Ab
APC Ab
APC Ab
APC Ab
APC Ab

产品简介

Product Introduction

Catalog No.

CY5641

Source

Recombinant Rabbit mAb

UniProt ID

P25054

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

312 kDa

Observed Mol Weight

170 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

APC; APC protein; Adenomatous polyposis coli protein; DP2.5; mAPC;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human APC

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton.

引用文献

Citation

No Data

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CY5641

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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