UBE2I Ab
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UBE2I Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
UBE2I Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
UBE2I Ab
Western blot analysis of UBE2I expression in HeLa cell lysate.
UBE2I Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using UBE2I Antibody.
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab

产品简介

Product Introduction

Catalog No.

CY5571

Source

Recombinant Rabbit mAb

UniProt ID

P63279

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

18 kDa

Observed Mol Weight

18 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

C358B7.1; P18; UBC9; UBE2I; SUMO1 protein ligase;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human UBE2I

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.

引用文献

Citation

Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication

期刊名称：

PLoS Pathogens

PMID：

38394330

影响因子：

5.5

应用范围：

WB

检测物种：

Pig

发表时间：

2024-02-23

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CY5571

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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