UBE2I Ab
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UBE2I Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
UBE2I Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
UBE2I Ab
Western blot analysis of UBE2I expression in HeLa cell lysate.
UBE2I Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using UBE2I Antibody.
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab
UBE2I Ab

产品简介

Product Introduction

Catalog No.

CY5571

Source

Recombinant Rabbit mAb

UniProt ID

P63279

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

18 kDa

Observed Mol Weight

18 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

C358B7.1; P18; UBC9; UBE2I; SUMO1 protein ligase;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human UBE2I

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.

引用文献

Citation

Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication

期刊名称：

PLoS Pathogens

PMID：

38394330

影响因子：

5.5

应用范围：

WB

检测物种：

Pig

发表时间：

2024-02-23

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CY5571

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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