ERK1/2 Ab
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ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ERK1/2 Ab
Western blot analysis of ERK1/2 Antibody expression in HepG2 whole cell lysates.
ERK1/2 Ab
Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo. -Food & Function
ERK1/2 Ab
Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. -Oncology Reports
ERK1/2 Ab
CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. -Molecular Cancer

产品简介

Product Introduction

Catalog No.

CY5487

Source

Recombinant Rabbit mAb

UniProt ID

P27361/P28482

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

43,41 kDa

Observed Mol Weight

42, 44 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ERK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

引用文献

Citation

Elevated expression of CXCL3 in colon cancer promotes malignant behaviors of tumor cells in an ERK-dependent manner

期刊名称：

BMC CANCER

PMID：

38031087

影响因子：

3.8

应用范围：

WB

检测物种：

Human

发表时间：

2023-11-29
Sophoridine Counteracts Obesity via Src-Mediated Inhibition of VEGFR Expression and PI3K/AKT Phosphorylation

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

38279206

影响因子：

4.9

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-01-19
Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells

期刊名称：

MOLECULAR AND CELLULAR BIOCHEMISTRY

PMID：

38980591

影响因子：

3.5

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-09
Impact of Air Pollutants on Lung Function and Inflammatory Response in Asthma in Shanghai

期刊名称：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES

PMID：

39198247

影响因子：

3

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-08-20

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CY5487

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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