ERK1/2 Ab
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ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ERK1/2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ERK1/2 Ab
Western blot analysis of ERK1/2 Antibody expression in HepG2 whole cell lysates.
ERK1/2 Ab
Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo. -Food & Function
ERK1/2 Ab
Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. -Oncology Reports
ERK1/2 Ab
CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. -Molecular Cancer

产品简介

Product Introduction

Catalog No.

CY5487

Source

Recombinant Rabbit mAb

UniProt ID

P27361/P28482

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

43,41 kDa

Observed Mol Weight

42, 44 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ERK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

引用文献

Citation

Mesenchymal stem cells maintain the stemness of colon cancer stem cells via interleukin-8/mitogen-activated protein kinase signaling pathway

期刊名称：

EXPERIMENTAL BIOLOGY AND MEDICINE

PMID：

32122165

影响因子：

3.139

应用范围：

WB,IHC

检测物种：

Human

发表时间：

2020-03-02
Mitophagy inhibitor liensinine suppresses doxorubicin-induced cardiotoxicity through inhibition of Drp1-mediated maladaptive mitochondrial fission

期刊名称：

PHARMACOLOGICAL RESEARCH

PMID：

32339784

影响因子：

5.893

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-04-25
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04
Up-regulation of CXCL8 expression is associated with a poor prognosis and enhances tumor cell malignant behaviors in liver cancer

期刊名称：

BIOSCIENCE REPORTS

PMID：

32766720

影响因子：

2.942

应用范围：

WB

检测物种：

Human

发表时间：

2020-08-20
USP18‑deficiency in cervical carcinoma is crucial for the malignant behavior of tumor cells in an ERK signal‑dependent manner

期刊名称：

Oncology Letters

PMID：

33850562

影响因子：

2.967

应用范围：

WB

检测物种：

Human

发表时间：

2021-03-29
Progesterone Suppresses Cholesterol Esterification in APP/PS1 mice and a cell model of Alzheimer’s Disease

期刊名称：

BRAIN RESEARCH BULLETIN

PMID：

34044033

影响因子：

4.079

应用范围：

ICC/IF,WB

检测物种：

Mouse,Rat

发表时间：

2021-05-25

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CY5487

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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