Focal adhesion kinase 1 Ab
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Focal adhesion kinase 1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Focal adhesion kinase 1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Focal adhesion kinase 1 Ab
Western blot analysis of FAK expression in HeLa cell lysate.
Focal adhesion kinase 1 Ab
Immunohistochemical analysis of paraffin-embedded mouse spleen, using FAK Antibody.
Focal adhesion kinase 1 Ab
Immunofluorescent analysis of Hela cells, using FAK Antibody.
Focal adhesion kinase 1 Ab
Focal adhesion kinase 1 Ab
Focal adhesion kinase 1 Ab

产品简介

Product Introduction

Catalog No.

CY5464

Source

Recombinant Rabbit mAb

UniProt ID

Q05397

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

119 kDa

Observed Mol Weight

119 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

FAK; FADK; FAK1; FRNK; pp125FAK; PTK2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Focal adhesion kinase 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.

引用文献

Citation

Interaction between CD9 and PI3K‑p85 activates the PI3K/AKT signaling pathway in B‑lineage acute lymphoblastic leukemia

期刊名称：

ONCOLOGY REPORTS

PMID：

34036396

影响因子：

3.906

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-26
MEKK4-mediated Phosphorylation of HOXA10 at Threonine 362 facilitates embryo adhesion to the endometrial epithelium

期刊名称：

Cell Death Discovery

PMID：

36216824

影响因子：

7.109

应用范围：

WB

检测物种：

Human

发表时间：

2022-10-10
FHL1 mediates HOXA10 deacetylation via SIRT2 to enhance blastocyst-epithelial adhesion

期刊名称：

Cell Death Discovery

PMID：

36418297

影响因子：

7.109

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-22
Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice

期刊名称：

EBioMedicine

PMID：

36623453

影响因子：

11.1

应用范围：

WB

检测物种：

Human

发表时间：

2023-01-07
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition

期刊名称：

Cell Communication and Signaling

PMID：

38689280

影响因子：

8.2

应用范围：

ICC/IF,WB

检测物种：

Rat

发表时间：

2024-04-30

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CY5464

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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