Bcl 2 L1 Ab
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Bcl 2 L1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Bcl 2 L1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Bcl 2 L1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Bcl 2 L1 Ab
Western blot analysis of Bcl-XL expression in (1) Ramos cell lysate; (2) K562 cell lysate.
Bcl 2 L1 Ab
Bcl 2 L1 Ab
Bcl 2 L1 Ab
Bcl 2 L1 Ab

产品简介

Product Introduction

Catalog No.

CY5452

Source

Recombinant Rabbit mAb

UniProt ID

Q07817

Reactivity

Human;Mouse;Rat

Application

WB;IHC;IP

Calculated Mol Weight

26 kDa

Observed Mol Weight

26 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

IP 1:20-1:50

Alternative Names

Apoptosis regulator Bcl-X; BLC2L; Bcl-2-like 1 protein bclxl; BCL2L; BCL2L1; BCLX;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Bcl 2 L1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

引用文献

Citation

Npc1 gene mutation abnormally activates the classical Wnt signalling pathway in mouse kidneys and promotes renal fibrosis

期刊名称：

ANIMAL GENETICS

PMID：

38087834

影响因子：

2.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-12-12

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CY5452

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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