Caspase 1 Ab - Abways

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Caspase 1 Ab

Instructions

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of Caspase-1 in HeLa cell lysate.

Immunohistochemical analysis of paraffin-embedded human liver, using Caspase-1 Antibody.

Introduction

Citation

User feedback

产品简介

Product Introduction

Catalog No.

CY5429

Source

Recombinant Rabbit mAb

UniProt ID

P29466

Reactivity

Human;Rat

Application

WB;IHC

Calculated Mol Weight

45 kDa

Observed Mol Weight

45 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

引用文献

Citation

Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca2+ release in vascular smooth muscle cells in diabetic mice

期刊名称：

LIFE SCIENCES

PMID：

32407845

影响因子：

3.647

应用范围：

WB,IHC,ICC/IF

检测物种：

Mouse

发表时间：

2020-05-11

Trimethylamine N-Oxide Exacerbates Renal Inflammation and Fibrosis in Rats With Diabetic Kidney Disease

期刊名称：

Frontiers in Physiology

PMID：

34220546

影响因子：

4.566

应用范围：

IHC

检测物种：

Rat

发表时间：

2021-06-16

Berberine Attenuates Hyperuricemia by Regulating Urate Transporters and Gut Microbiota

期刊名称：

AMERICAN JOURNAL OF CHINESE MEDICINE

PMID：

36266751

影响因子：

6.005

应用范围：

检测物种：

Mouse

发表时间：

2022-10-20

Discovery of Potent, Specific, and Orally Available NLRP3 Inflammasome Inhibitors Based on Pyridazine Scaffolds for the Treatment of Septic Shock and Peritonitis

期刊名称：

JOURNAL OF MEDICINAL CHEMISTRY

PMID：

39169676

影响因子：

6.8

应用范围：

检测物种：

Mouse

发表时间：

2024-08-21

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尾页

CY5429

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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