VDAC1 Ab
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VDAC1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
VDAC1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
VDAC1 Ab
Western blot analysis of VDAC1 expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate.
VDAC1 Ab
Immunohistochemical analysis of paraffin-embedded Mouse intestine, using the Antibody at 1:200 dilution.
VDAC1 Ab
Immunohistochemical analysis of paraffin-embedded Mouse skin, using the Antibody at 1:200 dilution.
VDAC1 Ab
Immunohistochemical analysis of paraffin-embedded Human stomach, using the Antibody at 1:200 dilution.
VDAC1 Ab
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:200 dilution.
VDAC1 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.

产品简介

Product Introduction

Catalog No.

CY5416

Source

Recombinant Rabbit mAb

UniProt ID

P21796

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

31 kDa

Observed Mol Weight

31 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

VDAC1;MGC111064;PORIN;PORIN-31-HL;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human VDAC1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.

引用文献

Citation

Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1

期刊名称：

EBioMedicine

PMID：

30093307

影响因子：

6.183

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2018-08-06
Cr (VI) induced mitophagy via the interaction of HMGA2 and PARK2

期刊名称：

TOXICOLOGY LETTERS

PMID：

32866567

影响因子：

3.569

应用范围：

WB

检测物种：

Human

发表时间：

2020-08-28
The crosstalk between mitochondrial dysfunction and endoplasmic reticulum stress promoted ATF4-mediated mitophagy induced by hexavalent chromium

期刊名称：

ENVIRONMENTAL TOXICOLOGY

PMID：

33650752

影响因子：

4.119

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2021-03-02
Melatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS

期刊名称：

Journal of Ovarian Research

PMID：

34758863

影响因子：

4.234

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-11-11
Ginsenoside Rb1 inhibits astrocyte activation and promotes transfer of astrocytic mitochondria to neurons against ischemic stroke

期刊名称：

Redox Biology

PMID：

35696763

影响因子：

10.787

应用范围：

WB

检测物种：

Rat

发表时间：

2022-06-08
HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

36116352

影响因子：

7.129

应用范围：

WB

检测物种：

Human

发表时间：

2022-09-15

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CY5416

Specifications：

50μl, 200μl

Price：

$100/50μl, $288/200μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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