CXCR4 Ab
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CXCR4 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
CXCR4 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
CXCR4 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
CXCR4 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
CXCR4 Ab
Western blot analysis of CXCR4 expression in Jurkat cell lysate.
CXCR4 Ab
Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, using CXCR4 Antibody.
CXCR4 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
CXCR4 Ab
Immunofluorescent analysis of Jurkat cells, using CXCR4 Antibody .

产品简介

Product Introduction

Catalog No.

CY5380

Source

Recombinant Rabbit mAb

UniProt ID

P61073

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

40 kDa

Observed Mol Weight

43 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CXCR4

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development.

引用文献

Citation

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CY5380

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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