ASK1 Ab
Instructions

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ASK1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ASK1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ASK1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
ASK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ASK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ASK1 Ab
Western blot analysis of ASK1 expression in HeLa cell lysates.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded Rat stomach, using the Antibody at 1:100 dilution.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded Human Hodgkin's lymphoma, using the Antibody at 1:100 dilution.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:100 dilution.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded Human astrocytoma, using the Antibody at 1:100 dilution.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded Mouse skin, using the Antibody at 1:100 dilution.
ASK1 Ab
Immunohistochemical analysis of paraffin-embedded human breast cancer, using ASK1 Antibody.

产品简介

Product Introduction

Catalog No.

CY5345

Source

Recombinant Rabbit mAb

UniProt ID

Q99683

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

155 kDa

Observed Mol Weight

155 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

Apoptosis signal- regulating kinase 1;ASK-1;MAP3K5;ASK1;MAPKKK5; MEK kinase 5;MEKK5;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ASK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens.

引用文献

Citation

Hepatoprotection of pine nut polysaccharide via NRF2/ARE/MKP1/JNK signaling pathways against carbon tetrachloride-induced liver injury in mice

期刊名称：

FOOD AND CHEMICAL TOXICOLOGY

PMID：

32540477

影响因子：

4.679

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-06-12

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CY5345

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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