Cathepsin D Ab
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Cathepsin D Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Cathepsin D Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Cathepsin D Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Cathepsin D Ab
Western blot analysis of Cathepsin D expression in (1)MCF-7 cell lysate;(2)SKBR-3 cell lysate.
Cathepsin D Ab
Immunohistochemical analysis of paraffin-embedded human ovarian cancer, using Cathepsin D Antibody.
Cathepsin D Ab
Cathepsin D Ab
Cathepsin D Ab

产品简介

Product Introduction

Catalog No.

CY5339

Source

Recombinant Rabbit mAb

UniProt ID

P07339

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

45 kDa

Observed Mol Weight

33 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Cathepsin D

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

引用文献

Citation

Swainsonine promotes apoptosis by impairing lysosomal function and inhibiting autophagic degradation in rat primary renal tubular epithelial cells

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

33186601

影响因子：

3.723

应用范围：

WB

检测物种：

Rat

发表时间：

2020-11-10
TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation

期刊名称：

Autophagy

PMID：

33618632

影响因子：

16.016

应用范围：

ICC/IF,WB

检测物种：

Mouse,Human

发表时间：

2021-03-03
Swainsonine inhibits autophagic degradation and causes cytotoxicity by reducing CTSD O-GlcNAcylation

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

37442287

影响因子：

5.1

应用范围：

WB

检测物种：

Rat

发表时间：

2023-07-11
Autophagic-lysosomal damage induced by swainsonine is protected by trehalose through activation of TFEB-regulated pathway in renal tubular epithelial cells

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

38579922

影响因子：

4.7

应用范围：

WB

检测物种：

Rat

发表时间：

2024-04-03

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CY5339

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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