ROCK1 Ab
Instructions

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ROCK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ROCK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ROCK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ROCK1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
ROCK1 Ab
Western blot analysis of ROCK1 expression in Ramos cell lysate.
ROCK1 Ab
Immunohistochemical analysis of paraffin-embedded Rat stomach, using the Antibody at 1:150 dilution.
ROCK1 Ab
Immunohistochemical analysis of paraffin-embedded Rat heart, using the Antibody at 1:150 dilution.
ROCK1 Ab
Immunohistochemical analysis of paraffin-embedded Human squamous carcinoma, using the Antibody at 1:150 dilution.

产品简介

Product Introduction

Catalog No.

CY5328

Source

Recombinant Rabbit mAb

UniProt ID

Q13464

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

158 kDa

Observed Mol Weight

158 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

p160 ROCK-1; p160-ROCK; p160ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho kinase; Rho-associated protein kinase 1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ROCK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A.

引用文献

Citation

Effects of RhoA on depression-like behavior in prenatally stressed offspring rats

期刊名称：

BEHAVIOURAL BRAIN RESEARCH

PMID：

35728732

影响因子：

3.352

应用范围：

WB

检测物种：

Rat

发表时间：

2022-06-18

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CY5328

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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