AMPK alpha 1 Ab

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AMPK alpha 1 Ab

Instructions

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Introduction

Citation

User feedback

产品简介

Product Introduction

Catalog No.

CY5326

Source

Recombinant Rabbit mAb

UniProt ID

Q13131

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

64 kDa

Observed Mol Weight

63 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

AMP-activate kinase alpha 1 subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AAPK1; AMPK; SNF1A; HMGCR kinase; PRKAA1; cb116;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human AMPK alpha 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolismIn response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.

引用文献

Citation

Inhibition of neointima hyperplasia by the combined therapy of linagliptin and metformin via AMPK/Nox4 signaling in diabetic rats

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

31369842

影响因子：

5.657

应用范围：

WB,ICC/IF,IHC

检测物种：

Rat

发表时间：

2019-07-29

Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish

期刊名称：

JOURNAL OF PHYSIOLOGY-LONDON

PMID：

32710562

影响因子：

4.547

应用范围：

检测物种：

Zebrafish

发表时间：

2020-07-25

Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

33065254

影响因子：

3.69

应用范围：

检测物种：

Rat

发表时间：

2020-10-13

Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function

期刊名称：

CELL RESEARCH

PMID：

34561619

影响因子：

25.617

应用范围：

WB,IP

检测物种：

Human,Mouse

发表时间：

2021-09-24

Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson’s disease

期刊名称：

METABOLIC BRAIN DISEASE

PMID：

34817756

影响因子：

3.584

应用范围：

检测物种：

Mouse

发表时间：

2021-11-24

Hydrogen sulfide protects retinal pigment epithelium cells against ferroptosis through the AMPK- and p62-dependent non-canonical NRF2-KEAP1 pathway

期刊名称：

EXPERIMENTAL CELL RESEARCH

PMID：

36435220

影响因子：

4.145

应用范围：

WB,IP

检测物种：

Human

发表时间：

2022-11-24

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尾页

CY5326

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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