beta Arrestin 1 Ab

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beta Arrestin 1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
beta Arrestin 1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
beta Arrestin 1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
beta Arrestin 1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
beta Arrestin 1 Ab
Western blot analysis of ARRB1 expression in 293T cell lysate.
beta Arrestin 1 Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using ARRB1 Antibody.
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab

产品简介

Product Introduction

Catalog No.

CY5314

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

47 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

ARRB1; ARB1; ARR1; Arrestin beta 1; Beta arrestin 1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.

引用文献

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CY5314

Specifications:

50μl, 150μl

Price:

$188/50μl, $368/150μl

Delivery time:

1-4 weeks

Ordering information:

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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