BIM Ab
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BIM Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BIM Ab
Western blot analysis of Bim expression in A431 cell lysate.
BIM Ab
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:100 dilution.
BIM Ab
Immunohistochemical analysis of paraffin-embedded Human esophageal carcinoma, using the Antibody at 1:100 dilution.
BIM Ab
Immunohistochemical analysis of paraffin-embedded human cervix cancer, using Bim Antibody.
BIM Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
BIM Ab
Immunofluorescent analysis of Raji cells, using Bim Antibody.
BIM Ab

产品简介

Product Introduction

Catalog No.

CY5307

Source

Recombinant Rabbit mAb

UniProt ID

O43521

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

22 kDa

Observed Mol Weight

22 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

BAM; BIM; BOD; BimL; BimS; BimEL; BIM-beta6; BIM-beta7; BIM-alpha6;BCL2L11;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BIM

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

引用文献

Citation

A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4′-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells

期刊名称：

CELL STRESS & CHAPERONES

PMID：

36242757

影响因子：

3.827

应用范围：

WB

检测物种：

Human

发表时间：

2022-10-15
Mitochondrial dysfunction and endoplasmic reticulum stress induced by activation of PPARα leaded testicular to apoptosis in SD rats explored to di-(2-ethylhexyl) phthalate (DEHP)

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

37979351

影响因子：

6.8

应用范围：

WB

检测物种：

Rat,Mouse

发表时间：

2023-11-17

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CY5307

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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