BIM Ab
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BIM Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
BIM Ab
Western blot analysis of Bim expression in A431 cell lysate.
BIM Ab
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:100 dilution.
BIM Ab
Immunohistochemical analysis of paraffin-embedded Human esophageal carcinoma, using the Antibody at 1:100 dilution.
BIM Ab
Immunohistochemical analysis of paraffin-embedded human cervix cancer, using Bim Antibody.
BIM Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
BIM Ab
Immunofluorescent analysis of Raji cells, using Bim Antibody.
BIM Ab
BIM Ab
BIM Ab
BIM Ab
BIM Ab

产品简介

Product Introduction

Catalog No.

CY5307

Source

Recombinant Rabbit mAb

UniProt ID

O43521

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

22 kDa

Observed Mol Weight

22 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

BAM; BIM; BOD; BimL; BimS; BimEL; BIM-beta6; BIM-beta7; BIM-alpha6;BCL2L11;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BIM

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

引用文献

Citation

A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4′-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells

期刊名称：

CELL STRESS & CHAPERONES

PMID：

36242757

影响因子：

3.827

应用范围：

WB

检测物种：

Human

发表时间：

2022-10-15
Mitochondrial dysfunction and endoplasmic reticulum stress induced by activation of PPARα leaded testicular to apoptosis in SD rats explored to di-(2-ethylhexyl) phthalate (DEHP)

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

37979351

影响因子：

6.8

应用范围：

WB

检测物种：

Rat,Mouse

发表时间：

2023-11-17

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CY5307

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target