mTOR Ab
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mTOR Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
mTOR Ab
Western blot analysis of mTOR expression in Jurkat cell lysate.
mTOR Ab
Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis. -Cellular Signalling
mTOR Ab
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II. -EXPERIMENTAL AND MOLECULAR MEDICINE
mTOR Ab
Taurine improves low‐level inorganic arsenic‐induced insulin resistance by activating PPARγ‐mTORC2 signalling and inhibiting hepatic autophagy. -JOURNAL OF CELLULAR PHYSIOLOGY
mTOR Ab
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry
mTOR Ab
Immunohistochemical analysis of paraffin-embedded rat liver, using mTOR Antibody.
mTOR Ab
mTOR Ab
mTOR Ab
mTOR Ab
mTOR Ab

产品简介

Product Introduction

Catalog No.

CY5306

Source

Recombinant Rabbit mAb

UniProt ID

P42345

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

289 kDa

Observed Mol Weight

289 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human mTOR

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals.MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins.Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2).In response to nutrients, growth factors or amino acids, mTORC1 is recruited to the lysosome membrane and promotes protein, lipid and nucleotide synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis .

引用文献

Citation

Overexpression of the 14-3-3γ protein in uterine leiomyoma cells results in growth retardation and increased apoptosis

期刊名称：

CELLULAR SIGNALLING

PMID：

29382566

影响因子：

3.487

应用范围：

WB

检测物种：

Human

发表时间：

2018-01-31
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy

期刊名称：

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PMID：

30308483

影响因子：

5.5

应用范围：

WB,ICC/IF,IHC

检测物种：

Rat

发表时间：

2018-10-11
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

期刊名称：

EXPERIMENTAL AND MOLECULAR MEDICINE

PMID：

31337748

影响因子：

4.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-07-23
Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-30
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04
Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)2D3 in hepatocellular carcinoma

期刊名称：

Cell Death Discovery

PMID：

35039485

影响因子：

7.109

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2022-01-17

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CY5306

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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