p-Rb (S780) Ab
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p-Rb (S780) Ab
Western blot analysis of Retinoblastoma phosphorylation expression in Jurkat cell lysate treated with Alkaline Phosphatase.
p-Rb (S780) Ab
p-Rb (S780) Ab
p-Rb (S780) Ab
p-Rb (S780) Ab
p-Rb (S780) Ab
p-Rb (S780) Ab
p-Rb (S780) Ab

产品简介

Product Introduction

Catalog No.

CY5260

Source

Recombinant Rabbit mAb

UniProt ID

P06400

Reactivity

Human

Application

WB;IHC

Calculated Mol Weight

106 kDa

Observed Mol Weight

110 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

OSRC; RB; p105-Rb; pRb; RB1; pp110; Retinoblastoma 1; PPP1R130

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human Rb around the phosphorylation site of S780

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Tumor suppressor that is a key regulator of the G1/S transition of the cell cycle. The hypophosphorylated form binds transcription regulators of the E2F family, preventing transcription of E2F-responsive genes.

引用文献

Citation

Down-regulation of RCC1 sensitizes immunotherapy by up-regulating PD-L1 via p27kip1/CDK4 axis in non-small cell lung cancer

期刊名称：

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

PMID：

33630417

影响因子：

5.31

应用范围：

WB

检测物种：

Human

发表时间：

2021-02-25

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CY5260

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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