STAT1 Ab
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STAT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
STAT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
STAT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
STAT1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
STAT1 Ab
Western blot analysis of STAT1 expression in HeLa cell lysate.
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab
STAT1 Ab

产品简介

Product Introduction

Catalog No.

CY5227

Source

Recombinant Rabbit mAb

UniProt ID

P42224

Reactivity

Human;Mouse

Application

WB;IP;FC

Calculated Mol Weight

87 kDa

Observed Mol Weight

84 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;ISGF3; CANDF7; STAT 1; Stat1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human STAT1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus.

引用文献

Citation

Bta-miR-2890 up-regulates JAK-STAT pathway to inhibit BoHV-1 replication by targeting viral gene UL41

期刊名称：

VETERINARY MICROBIOLOGY

PMID：

32456827

影响因子：

3.03

应用范围：

WB

检测物种：

Bovine,Human

发表时间：

2020-04-29
Nocardia rubra cell wall skeleton regulates tumour-associated macrophage polarization by reprogramming M2 macrophages into M1 macrophages via STAT1/STAT6 pathways

期刊名称：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY

PMID：

38441254

影响因子：

3.7

应用范围：

IHC,ICC/IF,WB

检测物种：

Human

发表时间：

2023-08-11
Overexpression of NLRP12 enhances macrophage immune response and alleviates herpes simplex keratitis

期刊名称：

Frontiers in Cellular and Infection Microbiology

PMID：

39119293

影响因子：

4.6

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-07-25

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CY5227

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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