MCAM Ab
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MCAM Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MCAM Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
MCAM Ab
Western blot analysis of CD146 expression in (1) A375 cell lysate;(2) HUVEC cell lysate.
MCAM Ab
Immunohistochemical analysis of paraffin-embedded human uterus, using CD146 Antibody.
MCAM Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
MCAM Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.
MCAM Ab
Immunofluorescent analysis of A375 cells, using CD146 Antibody.
MCAM Ab

产品简介

Product Introduction

Catalog No.

CY5209

Source

Recombinant Rabbit mAb

UniProt ID

P43121

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

72 kDa

Observed Mol Weight

120 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

A32 antigen; CD 146; CD146; CD146 antigen; Cell surface glycoprotein P1H12; Gicerin; MCAM; Melanoma adhesion molecule; Melanoma associated antigen A32;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MCAM

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.

引用文献

Citation

ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface

期刊名称：

ONCOGENE

PMID：

36528750

影响因子：

8.756

应用范围：

ICC/IF

检测物种：

Human

发表时间：

2022-12-17

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CY5209

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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