HIF 1 alpha Ab
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HIF 1 alpha Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
HIF 1 alpha Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
HIF 1 alpha Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
HIF 1 alpha Ab
Western blot analysis of HIF-1 alpha expression in Ramos cell lysate.
HIF 1 alpha Ab
Immunohistochemical analysis of paraffin-embedded human kindey, using HIF-1 alpha Antibody.
HIF 1 alpha Ab
Immunofluorescent analysis of Hela cells, using HIF-1 alpha Antibody.
HIF 1 alpha Ab
HIF 1 alpha Ab

产品简介

Product Introduction

Catalog No.

CY5197

Source

Recombinant Rabbit mAb

UniProt ID

Q16665

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

93 kDa

Observed Mol Weight

120 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

HIF1; MOP1; PASD8; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF1A

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human HIF 1 alpha

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions as a master transcriptional regulator of the adaptive response to hypoxia.Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.

引用文献

Citation

A genome-wide positioning systems network algorithm for in silico drug repurposing

期刊名称：

Nature Communications

PMID：

31375661

影响因子：

11.878

应用范围：

WB

检测物种：

Human

发表时间：

2019-08-02
Vitamin D suppress the production of vascular endothelial growth factor in mast cell by inhibiting PI3K/Akt/p38 MAPK/HIF-1α pathway in chronic spontaneous urticaria

期刊名称：

CLINICAL IMMUNOLOGY

PMID：

32339669

影响因子：

3.368

应用范围：

WB

检测物种：

Human

发表时间：

2020-04-25
The effect and mechanism of erianin on the reversal of oxaliplatin resistance in human colon cancer cells

期刊名称：

CELL BIOLOGY INTERNATIONAL

PMID：

34351659

影响因子：

3.612

应用范围：

WB

检测物种：

Human

发表时间：

2021-08-05
Hypoxia-activated XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of ΔNp63α expression and promote breast cancer metastasis independent of HIF1α

期刊名称：

CELL DEATH AND DIFFERENTIATION

PMID：

38413797

影响因子：

13.7

应用范围：

WB

检测物种：

Human

发表时间：

2024-02-27
Dihydroartemisinin breaks the positive feedback loop of YAP1 and GLUT1-mediated aerobic glycolysis to boost the CD8+ effector T cells in hepatocellular carcinoma

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

38754557

影响因子：

5.3

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2024-05-14

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CY5197

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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