MEK1/2 Ab
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MEK1/2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
MEK1/2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
MEK1/2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
MEK1/2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
MEK1/2 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
MEK1/2 Ab
Western blot analysis of MEK1/2 expression in (1) 293T cell lysate; (2) A549 cell lysate.
MEK1/2 Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using MEK1/2 Antibody.
MEK1/2 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
MEK1/2 Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
MEK1/2 Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.
MEK1/2 Ab
Immunofluorescent analysis of Hela cells, using MEK1/2 Antibody .
MEK1/2 Ab

产品简介

Product Introduction

Catalog No.

CY5168

Source

Recombinant Rabbit mAb

UniProt ID

Q02750/P36507

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

43,44 kDa

Observed Mol Weight

44 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK1, MP2K1, PRKMK1, kinase MEK1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MEK1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.

引用文献

Citation

CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04
MiR-184 Combined with STC2 Promotes Endometrial Epithelial Cell Apoptosis in Dairy Goats via RAS/RAF/MEK/ERK Pathway

期刊名称：

Genes

PMID：

32906580

影响因子：

3.759

应用范围：

WB

检测物种：

Human

发表时间：

2020-09-07
IL-35 enhances angiogenic effects of small extracellular vesicles in breast cancer

期刊名称：

FEBS Journal

PMID：

35037402

影响因子：

5.622

应用范围：

WB

检测物种：

Human

发表时间：

2022-01-17
Chaetoglobosin E inhibits tumor growth and promotes the anti-tumor efficacy of cytotoxic drugs in esophageal squamous cell carcinoma by targeting PLK1

期刊名称：

Annals of Translational Medicine

PMID：

36544631

影响因子：

3.616

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-01

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CY5168

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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