GRP78 BiP Ab
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GRP78 BiP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
GRP78 BiP Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GRP78 BiP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
GRP78 BiP Ab
Western blot analysis of GRP78 BiP expression in (1) HeLa cell lysate; (2) C6 cell lysate.
GRP78 BiP Ab
WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death. -bioRxiv
GRP78 BiP Ab
Immunohistochemical analysis of paraffin-embedded human testis, using GRP78 BiP Antibody.
GRP78 BiP Ab
GRP78 BiP Ab

产品简介

Product Introduction

Catalog No.

CY5166

Source

Recombinant Rabbit mAb

UniProt ID

P11021

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

72 kDa

Observed Mol Weight

78 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

GRP-78; GRP78; BIP; MIF2; HSPA5

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human GRP78 BiP

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate.

引用文献

Citation

The crosstalk between mitochondrial dysfunction and endoplasmic reticulum stress promoted ATF4-mediated mitophagy induced by hexavalent chromium

期刊名称：

ENVIRONMENTAL TOXICOLOGY

PMID：

33650752

影响因子：

4.119

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2021-03-02
CHOP Regulates Endoplasmic Reticulum Stress-Mediated Hepatoxicity Induced by Monocrotaline

期刊名称：

Frontiers in Pharmacology

PMID：

34108882

影响因子：

5.811

应用范围：

WB,ICC/IF

检测物种：

Rat

发表时间：

2021-05-24
Swainsonine Triggers Paraptosis via ER Stress and MAPK Signaling Pathway in Rat Primary Renal Tubular Epithelial Cells

期刊名称：

Frontiers in Pharmacology

PMID：

34447312

影响因子：

5.811

应用范围：

WB

检测物种：

Rat

发表时间：

2021-08-10
HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

36116352

影响因子：

7.129

应用范围：

WB

检测物种：

Human

发表时间：

2022-09-15
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4

期刊名称：

CHEMICO-BIOLOGICAL INTERACTIONS

PMID：

36473502

影响因子：

5.168

应用范围：

WB

检测物种：

发表时间：

2022-12-05
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration

期刊名称：

TOXICOLOGY

PMID：

39032683

影响因子：

4.8

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-19

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CY5166

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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