p-Mlkl (S345) Ab
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p-Mlkl (S345) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-Mlkl (S345) Ab
Western blot analysis of Phospho-MLKL (S345) expression in (1) L929 treated with Z-VAD + TNF alpha + SM164 cell lysate; (2) Untreated.
p-Mlkl (S345) Ab
p-Mlkl (S345) Ab
p-Mlkl (S345) Ab
p-Mlkl (S345) Ab
p-Mlkl (S345) Ab
p-Mlkl (S345) Ab

产品简介

Product Introduction

Catalog No.

CY5146

Source

Recombinant Rabbit mAb

UniProt ID

Q9D2Y4

Reactivity

Mouse

Application

WB;IP

Calculated Mol Weight

54 kDa

Observed Mol Weight

54 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

hMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from mouse Mlkl around the phosphorylation site of S345

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Does not have protein kinase activity.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

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CY5146

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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