Nrf 2 Ab
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Nrf 2 Ab
Western blot analysis of Nrf2 expression in 293T cell treated with arsenite.
Nrf 2 Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using Nrf2 Antibody.
Nrf 2 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Nrf 2 Ab
Immunofluorescent analysis of Hela cells, using Nrf2 Antibody.
Nrf 2 Ab
Nrf 2 Ab
Nrf 2 Ab
Nrf 2 Ab

产品简介

Product Introduction

Catalog No.

CY5136

Source

Recombinant Rabbit mAb

UniProt ID

Q16236

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF;IP;ChIP

Calculated Mol Weight

68 kDa

Observed Mol Weight

90-110 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP/ChIP 1:20-1:50

Alternative Names

Nuclear factor erythroid 2-related factor 2; Nuclear factor, erythroid derived 2, like 2; NFE2-related factor 2; NRF2; NF-E2-related factor 2; NFE2L2; NF2L2; HEBP1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Nrf 2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzymes, and promotes their expression, thereby neutralizing reactive electrophiles.

引用文献

Citation

Hepatoprotection of pine nut polysaccharide via NRF2/ARE/MKP1/JNK signaling pathways against carbon tetrachloride-induced liver injury in mice

期刊名称：

FOOD AND CHEMICAL TOXICOLOGY

PMID：

32540477

影响因子：

4.679

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-06-12
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells

期刊名称：

MOLECULAR NEUROBIOLOGY

PMID：

32770451

影响因子：

4.5

应用范围：

WB,ICC/IF

检测物种：

Human,Zebrafish

发表时间：

2020-08-08
Phytochemical characterization and hepatoprotective effect of active fragment from Adhatoda vasica Nees. against tert-butyl hydroperoxide induced oxidative impairment via activating AMPK/p62/Nrf2 pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

33065254

影响因子：

3.69

应用范围：

WB

检测物种：

Rat

发表时间：

2020-10-13
Sesamol ameliorates dextran sulfate sodium-induced depression-like and anxiety-like behaviors in colitis mice: the potential involvement of the gut–brain axis

期刊名称：

Food & Function

PMID：

35179534

影响因子：

6.317

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-02-11
Influence of dietary sodium taurocholate on the growth performance and liver health of Nile tilapia (Oreochromis niloticus)

期刊名称：

FISH PHYSIOLOGY AND BIOCHEMISTRY

PMID：

36044098

影响因子：

3.014

应用范围：

WB

检测物种：

Fish

发表时间：

2022-08-31
Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

36096356

影响因子：

8.101

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2022-09-10

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CY5136

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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