MLH1 Ab
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MLH1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MLH1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MLH1 Ab
Western blot analysis of MLH1 in 293T cell lysate.
MLH1 Ab
Immunohistochemical analysis of paraffin-embedded human colon, using MLH1 Antibody.
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab

产品简介

Product Introduction

Catalog No.

CY5109

Source

Recombinant Rabbit mAb

UniProt ID

P40692

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

85 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

DNA mismatch repair protein Mlh1; MutL protein homolog 1; COCA2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MLH1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

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CY5109

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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