MLH1 Ab
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MLH1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MLH1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MLH1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
MLH1 Ab
Western blot analysis of MLH1 in 293T cell lysate.
MLH1 Ab
Immunohistochemical analysis of paraffin-embedded human colon, using MLH1 Antibody.
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab

产品简介

Product Introduction

Catalog No.

CY5109

Source

Recombinant Rabbit mAb

UniProt ID

P40692

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

85 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

DNA mismatch repair protein Mlh1; MutL protein homolog 1; COCA2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MLH1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

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CY5109

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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