SMAD2 Ab
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SMAD2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SMAD2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SMAD2 Ab
Western blot analysis of Smad2 expression in (1) Jurkat cell lysate;(2) RAW264.7 cell lysate.
SMAD2 Ab
Immunofluorescent analysis of Hela cells, using Smad2 Antibody.
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab
SMAD2 Ab

产品简介

Product Introduction

Catalog No.

CY5090

Source

Recombinant Rabbit mAb

UniProt ID

Q15796

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;FC

Calculated Mol Weight

52 kDa

Observed Mol Weight

60 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

FC 1:20-1:100

Alternative Names

JV18-1; MADH2; MADR2; Mad-related protein 2; Mothers against DPP homolog 2; Smad 2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SMAD2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).

引用文献

Citation

In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin

期刊名称：

KOREAN JOURNAL OF INTERNAL MEDICINE

PMID：

32506869

影响因子：

2.751

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-06-09
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC)

期刊名称：

Journal of Gastrointestinal Oncology

PMID：

34532130

影响因子：

2.892

应用范围：

WB

检测物种：

Human

发表时间：

2021-08-01

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CY5090

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target