p21 CDKN1A Ab
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p21 CDKN1A Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
p21 CDKN1A Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p21 CDKN1A Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p21 CDKN1A Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p21 CDKN1A Ab
Western blot analysis of p21 in (1) MCF-7 cell lysate; (2) LnCaP cell lysate.
p21 CDKN1A Ab
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer. -Oncotarget
p21 CDKN1A Ab
Immunohistochemical analysis of paraffin-embedded human colon, using p21 Antibody.
p21 CDKN1A Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.

产品简介

Product Introduction

Catalog No.

CY5088

Source

Recombinant Rabbit mAb

UniProt ID

P38936

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

18 kDa

Observed Mol Weight

21 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; P21cip1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CDKN1A

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.

引用文献

Citation

Chaetoglobosin G inhibits proliferation, autophagy and cell cycle of lung cancer cells through EGFR/MEK/ERK signaling pathway

期刊名称：

PHARMAZIE

PMID：

33303057

影响因子：

1.198

应用范围：

WB

检测物种：

Human

发表时间：

2020-12-01
Interaction between CD9 and PI3K‑p85 activates the PI3K/AKT signaling pathway in B‑lineage acute lymphoblastic leukemia

期刊名称：

ONCOLOGY REPORTS

PMID：

34036396

影响因子：

3.906

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-26
IL-17A promotes endothelial cell senescence by up-regulating the expression of FTO through activating JNK signal pathway

期刊名称：

BIOGERONTOLOGY

PMID：

36463389

影响因子：

4.284

应用范围：

WB

检测物种：

Human

发表时间：

2022-12-03
MicroRNA-668-3p inhibits myoblast proliferation and differentiation by targeting Appl1

期刊名称：

BMC GENOMICS

PMID：

37488537

影响因子：

4.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-07-24
Eicosapentaenoic acid-mediated activation of PGAM2 regulates skeletal muscle growth and development via the PI3K/AKT pathway

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

38641281

影响因子：

7.7

应用范围：

WB

检测物种：

Pig

发表时间：

2024-04-17

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CY5088

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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