Caspase 9 Ab
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Caspase 9 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Caspase 9 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Caspase 9 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Caspase 9 Ab
Western blot analysis of Caspase-9 in HeLa cell lysate treated with Camptothecin.
Caspase 9 Ab
Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer. -OncoTargets and Therapy
Caspase 9 Ab
Immunohistochemical analysis of paraffin-embedded human liver cancer, using Caspase-9 Antibody.
Caspase 9 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Caspase 9 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Caspase 9 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Caspase 9 Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
Caspase 9 Ab
Immunofluorescent analysis of 3T3 cells, using Caspase-9 Antibody.
Caspase 9 Ab

产品简介

Product Introduction

Catalog No.

CY5049

Source

Recombinant Rabbit mAb

UniProt ID

P55211

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

46 kDa

Observed Mol Weight

48 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

APAF-3; Caspase9; ICE-LAP6; Apoptotic protease Mch-6; CASP-9; Caspase-9; Caspase-9 precursor; MCH6; RNCASP9;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 9

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

引用文献

Citation

Natural antisense transcript of hypoxia-inducible factor 1 regulates hypoxic cell apoptosis in epithelial ovarian cancer

期刊名称：

OncoTargets and Therapy

PMID：

30588022

影响因子：

2.656

应用范围：

WB

检测物种：

Human

发表时间：

2018-12-14
Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis

期刊名称：

BMC Complementary Medicine and Therapies

PMID：

32527252

影响因子：

0

应用范围：

WB

检测物种：

Rat

发表时间：

2020-06-11
Chlorogenic Acid as a Potential Therapeutic Agent for Cholangiocarcinoma

期刊名称：

Pharmaceuticals

PMID：

38931461

影响因子：

4.3

应用范围：

WB

检测物种：

Human

发表时间：

2024-06-17

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CY5049

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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