Caspase 8 Ab
Instructions

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Caspase 8 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Caspase 8 Ab
Western blot analysis of Caspase-8 expression in(1) Jurkat cell lysate; (2)HeLa cell lysate.
Caspase 8 Ab
Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer. - j cancer
Caspase 8 Ab
Immunofluorescent analysis using the Antibody at 1:200 dilution.
Caspase 8 Ab
Immunofluorescent analysis of K562cells, using Caspase-8 Antibody .
Caspase 8 Ab
Caspase 8 Ab
Caspase 8 Ab

产品简介

Product Introduction

Catalog No.

CY5038

Source

Recombinant Rabbit mAb

UniProt ID

Q14790

Reactivity

Human

Application

WB;ICC/IF

Calculated Mol Weight

55 kDa

Observed Mol Weight

55, 40 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

Alternative Names

FADD-like ICE; FLICE; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog; CAP4; Caspase-8 precursor;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 8

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood.Initiator protease that induces extrinsic apoptosis by mediating cleavage and activation of effector caspases responsible for FAS/CD95-mediated and TNFRSF1A-induced cell death.

引用文献

Citation

Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer

期刊名称：

Journal of Cancer

PMID：

31333785

影响因子：

3.182

应用范围：

WB

检测物种：

Human

发表时间：

2019-06-09

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CY5038

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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