GSK 3 beta Ab
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GSK 3 beta Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GSK 3 beta Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GSK 3 beta Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GSK 3 beta Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GSK 3 beta Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
GSK 3 beta Ab
All lanes use the Antibody at 1:1500 dilution for 1 hour at room temperature.
GSK 3 beta Ab
Western blot analysis of GSK3 beta expression in HEK293 cell lysate.
GSK 3 beta Ab
Immunohistochemical analysis of paraffin-embedded Human colon cancer, using the Antibody at 1:100 dilution.

产品简介

Product Introduction

Catalog No.

CY2434

Source

Recombinant Rabbit mAb

UniProt ID

P49841

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

47 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B; GSK3beta isoform;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human GSK 3 beta

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1.Requires primed phosphorylation of the majority of its substrates.

引用文献

Citation

Budding uninhibited by benzimidazoles 1 promotes cell proliferation, invasion, and epithelial-mesenchymal transition via the Wnt/β-catenin signaling in glioblastoma

期刊名称：

Heliyon

PMID：

37342577

影响因子：

4

应用范围：

WB

检测物种：

Human

发表时间：

2023-06-12
Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

期刊名称：

eLife

PMID：

38441416

影响因子：

6.4

应用范围：

WB,ICC/IF

检测物种：

Mouse,Human

发表时间：

2024-03-05

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CY2434

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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