BRCC3 Ab
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BRCC3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
BRCC3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
BRCC3 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab
BRCC3 Ab

产品简介

Product Introduction

Catalog No.

BY2243

Source

Rabbit pAb

UniProt ID

P46736

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IP;FC

Calculated Mol Weight

36 kDa

Observed Mol Weight

36 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Lys-63-specific deubiquitinase BRCC36;BRCA1-A complex subunit BRCC36;BRCA1/BRCA2-containing complex subunit 3;BRCA1/BRCA2-containing complex subunit 36;BRISC complex subunit BRCC36;BRCC36; C6.1A;CXorf53

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BRCC3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.Does not have activity toward 'Lys-48'-linked polyubiquitin chains.Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).

引用文献

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BY2243

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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