p-AKT1 (S473) Ab
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p-AKT1 (S473) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-AKT1 (S473) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-AKT1 (S473) Ab
Western blot analysis on 2 NIH/3T3 cell lysate treated with PDGF using Phospho-Akt(Ser473) Antibody.
p-AKT1 (S473) Ab
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry
p-AKT1 (S473) Ab
Fibulin-3 has anti-tumorigenic activities in cutaneous squamous cell carcinoma. -Journal of Investigative Dermatology
p-AKT1 (S473) Ab
Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. -Oncology Reports
p-AKT1 (S473) Ab
Immunohistochemical analysis of paraffin-embedded human kidney, using Phospho-Akt(Ser473) Antibody.
p-AKT1 (S473) Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.

产品简介

Product Introduction

Catalog No.

CY6569

Source

Recombinant Rabbit mAb

UniProt ID

P31749

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

56 kDa

Observed Mol Weight

60 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human AKT1 around the phosphorylation site of S473

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.

引用文献

Citation

Notoginsenoside R1 Ameliorates Cardiac Lipotoxicity Through AMPK Signaling Pathway.

期刊名称：

Frontiers in Pharmacology

PMID：

35370720

影响因子：

5.988

应用范围：

WB

检测物种：

Mouse,Rat

发表时间：

2022-03-17
Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway

期刊名称：

Frontiers in Pharmacology

PMID：

35401214

影响因子：

5.988

应用范围：

ICC/IF,WB

检测物种：

Rat,Human

发表时间：

2022-03-23
Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein

期刊名称：

CANCER BIOLOGY & THERAPY

PMID：

35816613

影响因子：

4.875

应用范围：

WB

检测物种：

Human

发表时间：

2022-07-11
Long noncoding RNA LIPH-4 promotes esophageal squamous cell carcinoma progression by regulating the miR-216b/IGF2BP2 axis

期刊名称：

Biomarker Research

PMID：

35971159

影响因子：

8.633

应用范围：

WB

检测物种：

Human

发表时间：

2022-08-16
miR-15a-5p enhances the malignant phenotypes of colorectal cancer cells through the STAT3/TWIST1 and PTEN/AKT signaling pathways by targeting SIRT4

期刊名称：

CELLULAR SIGNALLING

PMID：

36332797

影响因子：

4.85

应用范围：

WB

检测物种：

Human

发表时间：

2022-11-02
Coptidis rhizoma and evodiae fructus against lipid droplet deposition in nonalcoholic fatty liver disease-related liver cancer by AKT

期刊名称：

Chemical Biology & Drug Design

PMID：

37460115

影响因子：

3

应用范围：

WB

检测物种：

Human

发表时间：

2023-07-17

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CY6569

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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