p62 SQSTM1 Ab
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p62 SQSTM1 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
p62 SQSTM1 Ab
Western blot analysis of p62/SQSTM1 expression in SKBR-3 cell lysate.
p62 SQSTM1 Ab
Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells. -Toxicology
p62 SQSTM1 Ab
Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

产品简介

Product Introduction

Catalog No.

CY5546

Source

Recombinant Rabbit mAb

UniProt ID

Q13501

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

48 kDa

Observed Mol Weight

62 kDa

Recommended Dilution

WB 1:1000-1:5000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3;PDB 3; PDB3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Sequestosome 1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Molecular adapter required for selective macroautophagy (aggrephagy) by acting as a a bridge between polyubiquitinated proteins and autophagosomes.Promotes the recruitment of ubiquitinated cargo proteins to autophagosomes via multiple domains that bridge proteins and organelles in different steps.

引用文献

Citation

Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis

期刊名称：

Theranostics

PMID：

34522207

影响因子：

11.556

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2021-08-04
Obesity induced Ext1 reduction mediates the occurrence of NAFLD

期刊名称：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PMID：

34906902

影响因子：

3.575

应用范围：

WB

检测物种：

Human

发表时间：

2021-12-07
Repurposed antipsychotic chlorpromazine inhibits colorectal cancer and pulmonary metastasis by inducing G2/M cell cycle arrest, apoptosis, and autophagy

期刊名称：

CANCER CHEMOTHERAPY AND PHARMACOLOGY

PMID：

35067737

影响因子：

3.288

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2022-01-24
DDIT3 antagonizes innate immune response to promote bovine alphaherpesvirus 1 replication via the DDIT3-SQSTM1-STING pathway

期刊名称：

Virulence

PMID：

35259065

影响因子：

5.428

应用范围：

WB

检测物种：

Bovine

发表时间：

2022-03-08
Neospora caninum infection activated autophagy of caprine endometrial epithelial cells via mTOR signaling

期刊名称：

VETERINARY PARASITOLOGY

PMID：

35272252

影响因子：

2.821

应用范围：

WB,ICC/IF

检测物种：

Goat

发表时间：

2022-03-04
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis

期刊名称：

Acta Biomaterialia

PMID：

35447368

影响因子：

10.633

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-04-18

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CY5546

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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