SIRT1 Ab
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SIRT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
SIRT1 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
SIRT1 Ab
Western blot analysis of Sir2/SIRT1 expression in Jurkat cell lysate.
SIRT1 Ab
Immunohistochemical analysis of paraffin-embedded Rat stomach, using the Antibody at 1:100 dilution.
SIRT1 Ab
Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:100 dilution.
SIRT1 Ab
Immunohistochemical analysis of paraffin-embedded Human colon, using the Antibody at 1:100 dilution.
SIRT1 Ab
Immunohistochemical analysis of paraffin-embedded Human placenta, using the Antibody at 1:100 dilution.
SIRT1 Ab
Immunohistochemical analysis of paraffin-embedded Mouse lung, using the Antibody at 1:100 dilution.

产品简介

Product Introduction

Catalog No.

CY5023

Source

Recombinant Rabbit mAb

UniProt ID

Q96EB6

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

82 kDa

Observed Mol Weight

110 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

hSIR2; hSIRT1; NAD-dependent deacetylase sirtuin 1; SIR1; SIR2-like protein 1; SIR2L1; sirtuin 1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SIRT1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy.

引用文献

Citation

Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1

期刊名称：

CARCINOGENESIS

PMID：

34994384

影响因子：

4.741

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2022-01-05
Neospora caninum infection induced mitochondrial dysfunction in caprine endometrial epithelial cells via downregulating SIRT1

期刊名称：

Parasites & Vectors

PMID：

35915458

影响因子：

4.047

应用范围：

WB

检测物种：

Goat

发表时间：

2022-08-01
Si-Ni-San Reduces Hepatic Lipid Deposition in Rats with Metabolic Associated Fatty Liver Disease by AMPK/SIRT1 Pathway

期刊名称：

Drug Design Development and Therapy

PMID：

37808345

影响因子：

4.8

应用范围：

WB

检测物种：

Rat,Human

发表时间：

2023-12-31
Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

期刊名称：

Frontiers in Pharmacology

PMID：

38828455

影响因子：

4.4

应用范围：

WB,IP

检测物种：

Human

发表时间：

2024-05-17

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CY5023

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target