NR1H3 Ab
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NR1H3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NR1H3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NR1H3 Ab
Western blot analysis of LXR alpha expression in Jurkat cell lysate.
NR1H3 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
NR1H3 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
NR1H3 Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
NR1H3 Ab
NR1H3 Ab

产品简介

Product Introduction

Catalog No.

CY6866

Source

Recombinant Rabbit mAb

UniProt ID

Q13133

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;FC

Calculated Mol Weight

50 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

FC 1:20-1:100

Alternative Names

Liver X receptor alpha; LXR a; LXRA; NR1H3; RLD1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NR1H3

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

引用文献

Citation

Lupeol improves bile acid metabolism and metabolic dysfunction-associated steatotic liver disease in mice via FXR signaling pathway and gut-liver axis

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

38889641

影响因子：

6.9

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-06-17

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CY6866

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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