DR5 Ab
Instructions

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DR5 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
DR5 Ab
Western blot analysis of DR5 expression in HeLa cell lysate.
DR5 Ab
Immunoprecipitate (IP) analysis using the Antibody at 1:50 dilution. (wb at 1:6K dilution)
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab

产品简介

Product Introduction

Catalog No.

CY6877

Source

Recombinant Rabbit mAb

UniProt ID

O14763

Reactivity

Human

Application

WB;IP;FC

Calculated Mol Weight

48 kDa

Observed Mol Weight

40, 48 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DR5

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

引用文献

Citation

Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma

期刊名称：

PHYTOTHERAPY RESEARCH

PMID：

37525965

影响因子：

7.2

应用范围：

WB

检测物种：

Human

发表时间：

2023-08-01

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CY6877

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target