SKP2 Ab
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SKP2 Ab
Western blot analysis of SKP2 expression in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate.
SKP2 Ab
SKP2 Ab
SKP2 Ab
SKP2 Ab
SKP2 Ab
SKP2 Ab
SKP2 Ab

产品简介

Product Introduction

Catalog No.

CY7118

Source

Recombinant Rabbit mAb

UniProt ID

Q13309

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

48 kDa

Observed Mol Weight

48 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

FBL1; FLB1; FBXL1; MGC1366; SKP2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SKP2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.

引用文献

Citation

The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis

期刊名称：

Journal of Molecular Cell Biology

PMID：

28992327

影响因子：

5.988

应用范围：

WB

检测物种：

Human

发表时间：

2017-09-12

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CY7118

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All antibody products targeting this target

>> All rabbit monoclonal antibody products targeting this target