Lamin A/C Mouse mAb
Source: Monoclonal Antibodies Catalog No. : AB3304
Lamin A/C Mouse mAb (AB3304)
UniProt:P02545
Application:WB,ICC/IF
Reactivity:Human
Source:Mouse mAbhttp://www.abways.com/showproduct.asp?cid=AB3304
Data Sheet
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UniProt
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Mol Weight74/63KDa
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Alternative Names70 kDa lamin;LAMA,;LMN1;LMN C; lamin A/C; Lamin; HGPS; EMD2;
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ImmunogenPurified recombinant human LMNA protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionLamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the innernuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact withchromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role innuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:1000 ICC/IF 1:200
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Western blot detection of Lamin A/C in MCF7,A549 and Hela cell lysates using Lamin A/C mouse mAb (1:1000 diluted).Predicted band size:74,63KDa.Observed band size:74,63KDa. -
Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).
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