TDP43 Ab
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TDP43 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
TDP43 Ab
Immunohistochemical analysis of paraffin-embedded human glioma, using TDP43 Antibody.
TDP43 Ab
Immunofluorescent analysis of Hela cells, using TDP43 Antibody .
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab
TDP43 Ab

产品简介

Product Introduction

Catalog No.

DY1300

Source

Recombinant Rabbit mAb

UniProt ID

Q13148

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

45 kDa

Observed Mol Weight

45 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

ALS10; TAR DNA binding protein 43; TARDBP; TDP43;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TDP43

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

引用文献

Citation

HIV-1 Tat mediates microglial NLRP3 inflammasome activation and neurotoxicity by inducing cytosolic mtDNA stress

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

40494474

影响因子：

8.5

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2025-06-08

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DY1300

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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