KEAP1 Ab
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KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab

Immunofluorescent analysis using the Antibody at 1:25 dilution.

KEAP1 Ab
Immunofluorescent analysis using the Antibody at 1:100 dilution.
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab

产品简介

Product Introduction

Catalog No.

CY8804

Source

Recombinant Rabbit mAb

UniProt ID

Q14145

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

70 kDa

Observed Mol Weight

60-64 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:100

Alternative Names

Kelch-like ECH-associated protein 1;Cytosolic inhibitor of Nrf2;Kelch-like protein 19;INRF2;KIAA0132;KLHL19

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human KEAP1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination.KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes.

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CY8804

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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>> All rabbit monoclonal antibody products targeting this target