KEAP1 Ab
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KEAP1 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab

产品简介

Product Introduction

Catalog No.

CY8804

Source

Recombinant Rabbit mAb

UniProt ID

Q14145

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

70 kDa

Observed Mol Weight

60-64 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Kelch-like ECH-associated protein 1;Cytosolic inhibitor of Nrf2;Kelch-like protein 19;INRF2;KIAA0132;KLHL19

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human KEAP1

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination.KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes.

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CY8804

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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