NEDD4 Ab
Instructions

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NEDD4 Ab
Western blot analysis of NEDD4 expression in A549 cell lysate.
NEDD4 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab
NEDD4 Ab

产品简介

Product Introduction

Catalog No.

CY8238

Source

Recombinant Rabbit mAb

UniProt ID

P46934

Reactivity

Human;Mouse;Rat

Application

WB;IP;FC

Calculated Mol Weight

149 kDa

Observed Mol Weight

135 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Nedd4; PIG53; RPF1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human NEDD4

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity.

引用文献

Citation

VAPA suppresses BEFV and VSV-induced type I IFNs signaling response by targeting JAK1 for NEDD4-mediated ubiquitin-proteasome degradation

期刊名称：

VETERINARY MICROBIOLOGY

PMID：

40080976

影响因子：

2.4

应用范围：

WB

检测物种：

Human,Hamster

发表时间：

2025-03-04

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CY8238

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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