ASC Ab
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ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab
ASC Ab

产品简介

Product Introduction

Catalog No.

BY2922

Source

Rabbit pAb

UniProt ID

Q9ULZ3

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

22 kDa

Observed Mol Weight

22 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:10-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

PYCARD; ASC; CARD5; TMS; TMS-1; TMS1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ASC

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions as a key mediator in apoptosis and inflammation.Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner.Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3.

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BY2922

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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