ZIC2 Ab
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ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab
ZIC2 Ab

产品简介

Product Introduction

Catalog No.

BY2908

Source

Rabbit pAb

UniProt ID

O95409

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

55 kDa

Observed Mol Weight

56 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:10-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Zinc finger protein ZIC 2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human ZIC2

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.

引用文献

Citation

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BY2908

Specifications：

50μl, 150μl

Price：

$188/50μl, $368/150μl

Delivery time：

1-4 weeks

Ordering information：

You can contact authorized dealers to purchase Abways products and obtain technical support, or you can directly contact Abways China

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