PDHA1 Antibody
Source: Monoclonal Antibodies Catalog No. : CY6656
PDHA1 Antibody (CY6656)
UniProt:P08559
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（2）
http://www.abways.com/showproduct.asp?cid=CY6656
Data Sheet
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UniProt
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Mol Weight43kDa
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Alternative NamesPyruvate dehydrogenase E1 component subunit alpha, somatic form; mitochondrial; PDHE1-A type I; PDHA1; PHE1A;
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ImmunogenA synthesized peptide derived from human PDHA1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Catalyzes the removal of CO2 from pyruvate. Mutations in the α subunits of pyruvate dehydrogenase (E1) lead to congenital defects that are usually associated with lactic acidosis, neurodegeneration and early death.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Western blot analysis of PDHA1 expression in HeLa cell lysate.
References （2）
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice-Journal of Diabetes Research (J DIABETES RES)
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming-MOLECULAR CARCINOGENESIS
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