KAP1 Antibody
Source: Monoclonal Antibodies Catalog No. : CY5173
KAP1 Antibody (CY5173)
UniProt:Q13263
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.com/showproduct.asp?cid=CY5173
Data Sheet
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UniProt
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Mol Weight110kDa
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Alternative NamesE3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; KAP1; TF1B; RNF96; TIF1B; TRIM28;
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ImmunogenA synthesized peptide derived from human KAP1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionEnhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
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Western blot analysis of KAP1 expression in HeLa cell lysate. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature.
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